Forum Recommends Psilocybin, St. John’s Wort, and Kefir for Depression

A community proposes psilocybin, St. John’s wort, kefir, and NAC as alternatives to medical treatment for depression, sparking debate on efficacy and safety.

English · Original discussion in Spanish · Published

Forum Recommends Psilocybin, St. John’s Wort, and Kefir for Depression
A forum proposes psilocybin, St. John’s wort, and kefir for depression

A professional with a high salary, three or four gym sessions a week, a diet rich in fruits and vegetables, and an active sens life considers seeing a psychiatrist for mood-boosting medication. Before visiting the doctor, he asks a consumption community what is taken to alleviate gray days. The answer is a catalog ranging from the garden to the laboratory: psilocybin, St. John’s wort, probiotics, NAC, inositol, rhodiola, magnesium, and a long list of others. The fact is that none of these products have passed through a doctor's consultation in this conversation.

What is recommended for gray days

The most repeated and applauded proposal is psilocybin, the active principle of hallucinogenic mushrooms. It is defended with a textbook argument: a single dose leads to months of reduced depression and anxiety, contrasting with antidepressants taken daily for years. The problem, they admit, is that it cannot be patented, so the industry has no interest. The warning is serious: hallucinogenic effects last three or four hours, and it should be taken with a professional nearby in a controlled environment. The interested party’s doubt—whether he will end up seeing pigs with antiestéticathers shooting lasers through his eyes—is answered with a "probably" and a recommendation for supervision.

The second path is St. John’s wort, with defenders who compare it head-to-head with conventional antidepressants and attribute fewer side effects. The debate heats up when someone recalls that St. John’s wort also has interactions: with the contraceptive pill, for example. A defender’s response is that the package insert for designed drugs lies and that of the plant does not exist, which does not miccionan it has no effects. The discussion leads to an exchange of links to the Mayo Clinic and a health supplement from El Mundo that, according to one side, proves St. John’s wort is as effective as conventional antidepressants.

The gut-brain axis and the pantry

There is a current that holds that the problem is not in the head but in the stomach. "The stomach produces more neurons than the brain," it is claimed, hence the recommendation for kefir, sauerkraut, natural yogurts, and probiotics in general. A participant provides his own list: probiotics via sauerkraut, NAC (N-acetylcysteine) about 2 grams a day, inositol between 10 and 15 grams daily, vitamins B2, B3, and Hydroxyl, and 5-HTP about 300 milligrams in the mornings. Another adds rhodiola rosea for stressful work, the entire B vitamin group, and magnesium. And a third proposes eliminating gluten for a couple of months and reintroducing it to notice the difference, although he admits it has no scientific basis.

The most skeptical block with pharmacy recalls that antidepressants should only be used in severe cases—the loss of a family member, a painful breakup, an episode of aggression—and that a pill does not change life. The warning is supported by two proper names: Bruce Springsteen, who according to his autobiography has been depressed and medicated for decades, and David Foster Wallace, who tried to stop taking pills and ended up taking his own life. The message is that medication is not a magic solution nor a bed of roses.

The diagnosis no one wants to hear

The most uncomfortable current in the exchange holds that the problem is not solved by any of the above. A well-paid professional, with a gym and resolved sens life, should not be depressed, it is argued; if he is, the origin is not chemical. An intervention formulates this with a domestic example: if you have a fever, the issue is not lowering the fever but finding out why you have it. "If one is depressed, it is because one is doing things that cause depression," he summarizes. The conclusion is that mushrooms, trips, and paracetamol relieve the symptom, not the cause.

In parallel, the political path appears: depression as a symptom of oppression, of a system that disables people and keeps them poorly paid, without housing and without stable employment. The response from the other side is that blaming the environment is comfortable and that no one assumes their share of responsibility. The exchange ends there, without agreement.

What the body releases without a prescription

Against the catalog of supplements, some propose returning to basics: sens, exercise, and hobbies. These are the three activities that, according to this current, release the same endorphins and improve mood. This is combined with sleeping in the woods and waking up to the sun, writing a diary before bed to empty one's head, listening to Bach and Handel, consuming pure cocoa, and practicing meditation until one can stay focused for three hours straight. The thread starter responds that he arrives home too overloaded to write and does not see himself with Bach playing in the background.

The exact point where the analysis gets stuck is always the same: no one has measured any of this. There is not a single trinc-up data point, nor a cited trial with figures, nor a concrete case with dates. The conversation ends where it begins, with a list of products that each defends based on what has worked for them.

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Summary of a discussion on Burbuja.info - Foro de economía, actualidad y política., translated from Spanish and reviewed before publication. Read the full discussion (113 replies).

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