The dilemma of parenthood with cancer and bipolar disorder: what are the odds of inheritance?
Deciding to have a child while carrying a cancer history and a bipolar disorder diagnosis is no trivial matter: genetic inheritance figures are the first hurdle. A person who has overcome cancer and lives with bipolar disorder asked in a forum what the real risk is of passing both conditions on to a child. The answers, based on studies and estimates, paint a complex picture where the numbers do not always bring comfort.
Bipolar disorder figures: between 1% and 5%
Bipolar disorder affects roughly 1% of the general population, a conservative estimate. However, for children of mothers with the disorder, the risk multiplies: studies cite an increase of between 1.3 and 2.5 times, which would put the probability at 3-5%. In other words, out of every 20 children of mothers with bipolar disorder, one may develop the condition. The heritability of bipolar disorder is estimated at 70%, according to sources cited in the analysis.
Cancer: a more diffuse inheritance
When it comes to cancer, the figures are less precise. It is suggested that one third of cancers are due to lifestyle and two thirds to environment and genetics, although this division is disputed. For example, hereditary colon cancer accounts for only 5% of cases, while other types may carry a much heavier genetic load. The absence of a single figure means risk must be assessed case by case. One analysis noted that one in three or four people will develop cancer over their lifetime, regardless of family history.
The decision beyond the statistics
Against the numbers stand opposing views. Some argue that love and care outweigh any probability, pointing out that we all inherit good and bad genetic cards. Others point to adoption as an alternative to avoid suffering. One comment summed it up bluntly: "The least likely way for your child to inherit an illness is not to have them." The final decision, pending broader studies, remains a leap into the void with eyes wide open.
Summary of a discussion on Burbuja.info - Foro de economía, actualidad y política., translated from Spanish and reviewed before publication.
Read the full discussion (16 replies).